Researchers have unveiled the intricate molecular mechanisms governing TCF/LEF-mediated transcription in the canonical Wnt pathway, identifying these proteins as promising therapeutic targets for ...
This cover highlights the article Macrophage metabolic reprogramming during dietary stress influences adult body size in Drosophila by Tina Mukherjee, Anusree Mahanta and colleagues. The cover artwork ...
Targeting the WNT signaling pathway represents a promising strategy for cancer therapy. The field has evolved to include numerous inhibitors currently under preclinical and clinical investigation.
Wnt signaling pathways have many important roles in cells and are highly conserved across the animal kingdom from fruit flies to humans. In addition to Wnt signaling being involved in many processes ...
On today’s college campuses, students are not maturing — they’re managing. Beneath a facade of progressive slogans and institutional virtue-signaling lies a quiet psychological crisis, driven by the ...
1 Chengdu Integrated TCM and Western Medicine Hospital, Department of Traditional Chinese Medicine Pharmacy, Chengdu, China 2 Henan University of Traditional Chinese Medicine, Department of ...
Lucas Kloberdanz-Dyck is a writer for Collider. He grew up creating lists, stories, and worlds, which led to his love of anime and video games. He attended Sheridan College where he earned an Honours ...
To investigate whether activating the Wnt/β-catenin signalling pathway differentially promotes fracture healing in aged and adult individuals. CatnbTM2Kem, Catnblox(ex3) and wild-type adult and aged ...
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Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...
The Wnt signaling pathway controls cell polarity, although the role of Wnts themselves remains controversial. This important study addresses the involvement of the Wnt pathway in the specification and ...