We’re all mostly human. 8% of your genome comes from viruses. In A Nutshell Scientists captured the first detailed images of ...

CpG density and epigenetic modification state modulate DNA mechanics, altering its intrinsic compatibility with nucleosome formation.

Deutsche Bank (DB) said bitcoin’s BTC $93,711.70 slide to about $80,000 on Nov. 21, roughly 35% below its early-October peak, shows how quickly macroeconomic pressures and fragile market structure can ...

The ScienceCodons PDB Viewer is a high-performance tool for visualizing, analyzing, and exploring macromolecular structures directly in your web browser. It offers seamless support for PDB, mmCIF, and ...

Accessible to all, millions of scientists, doctors, researchers and students around the world access the RCSB PDB annually. The RCSB PDB Molecule of the Month presents short accounts on selected ...

For decades, structural biologists have relied on specialized file formats to store and exchange the detailed three-dimensional coordinates of macromolecules. Among these, the most widely recognized ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Per- and polyfluoroalkyl substances (PFAS) are persistent environmental pollutants ...

Illustration showing how integrating protein three-dimensional structures with artificial intelligence algorithms can predict synergistic or antagonistic effects of drug combinations, guiding safer ...

Drug developers have historically glued their attention to targeting the precise and fine-tuned protein structures underlying biological function. Yet this approach misses over 50% of the human ...

This valuable work presents an interpretable protein-DNA Energy Associative (IDEA) model for predicting binding sites and affinities of DNA-binding proteins. While the method is convincing, it ...

*Note: One patient in each cohort finished treatment without at least one post-baseline tumor assessment. Among the patients with PD-L1 TPS<1%, IBI363 demonstrated outstanding efficacy signals: in the ...