Membrane proteins and membrane lipids are essential partners in various biological processes, and elucidating their ...

Let's be honest, we're all drama queens sometimes. Whether you're texting your bestie you're “literally dying” over the latest celebrity gossip or declaring on social media that Monday mornings are ...

Cell membranes cradle, protect, and gatekeep living cells. Membranes can even affect how a cell behaves. But membranes' own erratic behavior has puzzled scientists for years. Turns out, it's all about ...

If your blood contains too much of the waxy substance called cholesterol, your risk of a heart attack or stroke from a clogged artery goes up. You may have inherited your high cholesterol, but diet ...

This rare lung condition can happen when fat (lipids) builds up in your lungs. Here's an overview, including its types, causes, treatments, and ways to help prevent it. Vaping can cause you to develop ...

The lipid asymmetry of the plasma membrane and its regulated release through lipid scrambling are critical determinants of membrane properties and functions. Such scrambling occurs during many ...

A new class of lipids improve the rates at which lipid nanoparticles (LNPs) successfully deliver RNA therapeutics and gene editing tools, promising to increase their effectiveness of such treatments.

An illustration showing a lipid nanoparticle containing messenger RNA enter a cell. A lipid nanoparticle (LNP) containing messenger RNA (mRNA) enters a cell through an endosome (right). When the LNP ...

LNPs are solid or semi-solid particles at room temperature. They are composed of a lipid core stabilized by surfactants or other agents. This lipid core provides a hydrophobic environment ideal for ...

To create A1 lipid nanoparticles for delivering mRNA to target cells, scientists at the University of Pennsylvania used A3 coupling. A3 refers to the amine–aldehyde–alkyne coupling reaction, which the ...