Since its introduction by Polly Matzinger, the Danger Theory has profoundly reshaped modern immunology. Rather than relying solely on a self/non-self ...

Scientists have made a discovery that helps explain why humans and animals are so susceptible to contracting tuberculosis (TB ...

aps the immune cell landscape of bone marrow in patients with multiple myeloma, a rare cancer that develops in the plasma ...

A giant functional atlas of immune cells in a Chinese cohort reveals crucial differences with European and Japanese data sets ...

Janux Therapeutics develops intratumoral immuno-oncology therapies as nasdaq 100 index discussions highlight biotech ...

Apogee Therapeutics develops RORγt-targeted therapies as Nasdaq today highlights clinical-stage biotech activity.

The microbiome not only consists of bacteria, but also of fungi. Most of them support human and animal health. However, some fungi also have pathogenic potential. For instance, the yeast Candida ...

Researchers revealed that the microbial metabolite TMA can directly block the immune protein IRAK4, reducing inflammation and improving insulin sensitivity. The molecule counteracts damage caused by ...

A new nasal-delivered nanotherapy shows promise against aggressive glioblastoma tumors. By activating the STING immune pathway using gold-core spherical nucleic acids, researchers were able to reach ...

A new study led by University of Toronto researchers has shown that immune cells in the gut follow an atypical pathway to produce antibodies that provide long-term protection against viruses. The ...

In a highly anticipated article, FDA officials Vinay Prasad, M.D., and Martin Makary, M.D., outlined a novel regulatory pathway that could trigger a seismic shift in how bespoke gene editing therapies ...

The researchers used lipid nanoparticles (LNPs) to deliver cyclic GMP-AMP (cGAMP) synthase (cGAS) mRNA to cancer cells. This results in production of the endogenous stimulator of interferon genes ...