CAMBRIDGE, MA -- By stimulating cancer cells to produce a molecule that activates a signaling pathway in nearby immune cells, MIT researchers have found a way to force tumors to trigger their own ...
Scientists generally agree that eukaryotes, the domain of life whose cells contain nuclei and that includes almost all multicellular organisms, originated from a process involving the symbiotic union ...
Figure 1. The framework of host immunological pathways and their relation to programmed cell death. Apoptosis is related to host anti-virus eradicable THαβ immunity. Autophagy is related to host ...
The researchers used lipid nanoparticles (LNPs) to deliver cyclic GMP-AMP (cGAMP) synthase (cGAS) mRNA to cancer cells. This results in production of the endogenous stimulator of interferon genes ...
New findings reveal how cancer manipulates immune pathways and highlight therapeutic strategies to unleash T-cells against even the most resistant tumors. Study: Cancer cells impair monocyte-mediated ...
Laura holds a Master's in Experimental Neuroscience and a Bachelor's in Biology from Imperial College London. Her areas of expertise include health, medicine, psychology, and neuroscience.View full ...
In this study, scientists looked at joint tissue biopsies from patients in the early stages of RA. They found a suite of proteins used by the immune system to attack pathogens. The process is often ...
Subscribe to our newsletter for the latest sci-tech news updates. Activating this signaling pathway, known as the cGAS-STING pathway, worked even better when combined with existing immunotherapy drugs ...