Proteins are the end products of the decoding process that starts with the information in cellular DNA. As workhorses of the cell, proteins compose structural and motor elements in the cell, and they ...

The positions of these water molecules are often important for understanding protein flexibility and the ability of drug-like molecules to influence protein structure and function. In this study, ...

On Wednesday, the Nobel Committee announced that it had awarded the Nobel Prize in chemistry to researchers who pioneered major breakthroughs in computational chemistry. These include two researchers ...

In the rapidly advancing field of computational biology, a newly peer-reviewed review explores the transformative role of deep learning techniques in revolutionizing protein structure prediction. The ...

Solving puzzles experimentally is enjoyable for many researchers. However, there are some puzzles that force even the best puzzlers to nominate modeling over experimental approaches to help decipher ...

With MassiveFold, scientists have unlocked AlphaFold's full potential, making high-confidence protein predictions faster and more accessible, fueling breakthroughs in biology and drug discovery. Brief ...

The sensory receptor PIEZO1 changes shape in response to mechanical stimuli. The super high-resolution microscopy technology used in this discovery is a breakthrough in enabling protein structures to ...