A causative role for Notch signalling is well established in T cell acute lymphoblastic leukaemias (T-ALLs), which have activating mutations in the Notch genes resulting in a constitutively active ...

The role of the Notch pathway during animal neural development is best understood in fruit flies, where Notch has been shown to inhibit differentiation by lateral signaling and regulate cell fate ...

Notch signalling is involved in the cell-cell communication process via influencing the patterns of gene expression and differentiation. Notch pathway maintains stem cell populations and regulates ...

The notch signaling pathway plays a major role in regulating various cellular processes during development, therefore dysregulation of this pathway can lead to disease. This basic signaling pathway ...

Essential did it first. Apple made it bigger and bolder. Now the rest of the smartphone world is playing me-too. So who “owns” the notch? And more to the point: who even wants to? As bezels decrease ...