AKT, protein kinase B; BAX, B-cell lymphoma-2-related protein X; cGAMP, cyclic-guanosine monophosphate-adenosine monophosphate; cGAS, cGAMP synthase; dsDNA, double ...

A protein called STING, previously shown to control a pathway that contributes to antiviral signaling, also plays an important role in cellular stress clearance and cell survival, according to a new ...

Researchers have been exploring ways to activate the cGAS/STING pathway in tumors as a way to slow their growth.

The cGAS-STING pathway facilitates crosstalk between cancer cells and the tumor microenvironment (TME). The activation of cGAS-STING promotes the release and presentation of cancer antigens, T cell ...

Researchers have long focused on the STING (Stimulator of Interferon Genes) pathway as a way to harness the immune system's natural defenses against cancer. This pathway, which plays a key role in ...

Subscribe to our newsletter for the latest sci-tech news updates. Activating this signaling pathway, known as the cGAS-STING pathway, worked even better when combined with existing immunotherapy drugs ...