Scientists at the Icahn School of Medicine at Mount Sinai have developed a lipid nanoparticle system capable of delivering messenger RNA (mRNA) to the brain via intravenous injection, a challenge that ...
A new study shows that lipid nanoparticles restructure their membrane significantly after being absorbed into a cell and ...
Just as a chef perfects a dish by experimenting with flavors and textures, the researchers used an iterative process, testing variations to find the ideal structure for the ionizable lipid. This lipid ...
The development of acid degradable linkers that rapidly hydrolyze at endosomal pHs is a central problem in the field of drug delivery. Acid degradable linkages are challenging to develop because of ...
Researchers at the Icahn School of Medicine at Mount Sinai have developed a lipid nanoparticle system capable of delivering messenger RNA (mRNA) to the brain via intravenous injection, bypassing the ...
Penn Engineers have discovered a novel means of directing lipid nanoparticles (LNPs), the revolutionary molecules that delivered the COVID-19 vaccines, to target specific tissues, presaging a new era ...
Scientists at the Icahn School of Medicine at Mount Sinai have developed a lipid nanoparticle system capable of delivering messenger RNA (mRNA) to the brain via intravenous injection, a challenge that ...
A study from FAU has shown that lipid nanoparticles restructure their membrane significantly after being absorbed into a cell ...
Top Left: Distribution of vaccines, "Naked mRNA" and "mRNA cloaked in a lipid coat." Bottom Left: Lung tissues in unvaccinated and vaccinated mice after SARS-CoV-2 challenge. Right: Schematic diagram ...
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