Study suggests that persistently activated ATF6α is a tumor driver, a potential stratification marker for immunotherapy response, and a therapeutic target for HCC.

Researchers at City St. George’s, University of London, have identified a new molecular signature that may explain why ...

The following filter criteria for genes differentially expressed were used: PDAC versus normal pancreas (bulk tissue), PDAC versus normal pancreas (microdissected normal ductal cells), and PDAC versus ...

Why do some tumors spread while others remain localized? The mechanisms governing the metastatic potential of tumor cells ...

Despite spanning about three billion base pairs, the human genome is wrapped up tight in a highly organized fashion in the nucleus. This coordinated structure, in part, enables the cell to regulate ...

What if a cup of coffee could help treat cancer? Researchers at the Texas A&M Health Institute of Biosciences and Technology ...

Scientists at St. Jude Children's Research Hospital have revealed previously unappreciated roles for the retrotransposon LINE-1 in shaping the cancer genome structure and regulation. Retrotransposons ...

Deep-learning model decodes the regulatory effects of DNA changes ...

New research shows a common skin fungus can help melanoma spread by changing cancer cell movement and energy use.

In this global network study, researchers examined vitamin B12 levels as a possible biomarker for outcomes in colon cancer.