Nature

Detection and significance of human papillomavirus, CDKN2A(p16) and CDKN1A(p21) expression in squamous cell carcinoma of the larynx

As the relationship between HPV and squamous cell carcinoma of the oropharynx unfolds, the significance of HPV in non-oropharyngeal head and neck squamous cell carcinoma remains less certain. In the ...
Nature

Concordant loss of MTAP and p16/CDKN2A expression in pancreatic intraepithelial neoplasia: evidence of homozygous deletion in a noninvasive precursor lesion

One of the most important of the genetic alterations in infiltrating adenocarcinoma of the pancreas and in PanIN, as judged by its high prevalence, is inactivation of the p16 gene. The p16 gene is ...
Healio

CDKN2A mutation surveillance leads to earlier pancreatic cancer detection

Please provide your email address to receive an email when new articles are posted on . Surveillance of patients carrying the CDKN2A gene mutation led to earlier detection of pancreatic ductal ...
ascopubs.org

Correlation of polymorphic variants into the susceptibility of CDKN2 locus with melanoma outcome.

Prognostic factors for survival after first recurrence of melanoma. Methods: Nine SNPs spanning the CDKN2 locus were investigated jointly by logistic regression among 383 healthy controls and 396 ...
ascopubs.org

Role of the p16 tumor suppressor gene in cancer.

Molecular abnormalities in lung cancer. Health-related quality of life in the general Norwegian population assessed by the European Organization for Research and Treatment of Cancer Core ...