Extract: Glucuronide conjugation of bilirubin in mammalian liver is catalyzed by the microsomal enzyme uriding phosphoglucuronyltransefrasc (UDPGT). Enzymic activity as measured in vitro is low in the ...

RECENT clinical studies have demonstrated that osmotic diuresis, with or without urinary alkalinization, will accelerate the renal excretion of drug in patients with barbiturate intoxication. 1–5 When ...

Barbiturates are synthetic drugs used in medicine to depress the central nervous system (CNS). The effects of barbiturates range from mild sedation to coma, with their indications ranging from ...

Barbiturates are a kind of depressant or sedative drug. They are an old class of drug used to relax the body and help people sleep. These drugs were first developed in the late 19th century. Use of ...

RECENT clinical studies have demonstrated that osmotic diuresis, with or without urinary alkalinization, will accelerate the renal excretion of drug in patients with ...